Improve your chances of getting pregnant and save money

Whether or not you have been diagnosed with PCOS, the chances are that Replenitol can help you achieve your goal of becoming pregnant. It corrects a metabolic deficiency that is quite marked among most women with PCOS and which may also affect all women (and men) to a lesser degree. So it may be symptomless in most regards but presents a challenge to getting pregnant. The metabolite in question is the active ingredient in Replenitol, myo-inositol NF12, which is absolutely essential for normal egg development in women and for sperm development in men.

Getting to the root cause of the problem

Most women with PCOS have close relatives who also have or had the condition and/or type 2 diabetes. A key characteristic of both syndromes is insulin resistance which causes the pancreas to produce excessive insulin.

A diet with an excess of carbohydrates also produces the same effect and can, over time, lead to a deficiency of the crucial metabolite involved in insulin signalling and which is also essential for normal sperm and egg production. A deficiency can cause the disruption of normal blood sugar regulation, cholesterol and sex hormones - typically observed in PCOS and type 2 diabetes. A disturbance in the normal pathways caused by a genetic predisposition and/or high carbohydrate diet can have a profound negative impact on your fertility. Replenitol replenishes the body's access to the missing metabolite and can correct the disrupted systems, including restoration of fertility.

Replenitol directly supplements the deficiency, normal biochemical control returns and the impaired fertility is reversed

Replenitol is part of the only therapy grouping that directly addresses the defect: it corrects the cause of insulin resistance at source. It replenishes the body's supply of the critical metabolite, myo-inositol, which is essential for blood sugar regulation and the normal development of follicles and sperm. The active ingredient is entirely natural and there are no known side effects or interactions with other treatments. Our bodies produce 4g per day to meet our needs for this essential building block - any excess is simply excreted.

If we become deficient, the normal control of blood sugars, cholesterol and sex hormones can become disrupted leading to impaired fertility. If your blood cholesterol is in the high normal range, this could be an indication that your reserves are depleted which is impairing your fertility. Replenitol ensures that the follicles and sperm are fully supplied with the metabolites essential for normal gamete production, boosting fertility.

The effectiveness of Replenitol in PCOS has been known for many years. More recently, studies have highlighted its potential role in helping all women and men conceive. Our modern diet, which is high in carbohydrates, can deplete an essential metabolite that is needed for normal levels of fertility and, as we age, this depletion can worsen, presenting a major challenge to having a baby. Often, medical intervention is required to help those affected complete their families. This usually involves a course of ovarian stimulation by daily injections of FSH and implantation of embryos produced in a laboratory environment.

Two recent studies demonstrated that women taking a 3-month course prior to commencement of a treatment cycle produced a greater proportion of top quality oocytes, had greater ovarian sensitivity and showed a trend toward improved pregnancy rates. Larger studies are required to prove statistical significance of this effect. Here, you can see how Replenitol can help:

Pretreatment reduces the number of days that a women will have to inject herself with FSH and lowers the total dose by 12-19% - saving money as well as increasing oocyte quality. There is a trend to increased pregnancy rates that may be confirmed by larger studies. Reducing the amount of FSH administered lowers both the risk of ovarian hyperstimulation and the chances of cancellation of the treatment cycle which can improve the chances of conceiving and saving money: the average saving more than outweighs the cost of 3 months of treatment with Replenitol.

Women with PCOS benefit more markedly

A prospective, controlled, randomised trial among 196 sub-fertile women with PCOS assessed the benefits of myo-inositol pretreatment in ART outcomes. The results demonstrated positive biochemical changes leading to highly significant improvements in clinical outcomes.

Women presenting with insulin resistance showed a significant reduction in cancellation rate whilst the trend for improvement was still observed in women with normal insulin control.

51.2% more pregnancies

58.5% fewer cancelled cycles

3½ fewer injection days

among women with PCOS undergoing ART

Treatment Group Outcomes

• 9 Spontaneous Pregnancies prior to ART

• 15% reduction in total FSH dose

• Treatment Duration reduced by 3½ days

• 51% more Clinical Pregnancies

• 58.5% fewer Cancelled Cycles